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Notes on doing it properly.

Short pieces on methodological decisions that change the outcome of a study. Written for whoever will use the figure, not for whoever produces it.

  • Methodological note · 2026

    Why a sample of 150 physicians cannot read six segments

    The most common error in pharmaceutical research is not in the field, it is in the cut. How to size a sample when segment-level analysis is the real objective.

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  • Analysis · 2026

    The eligible universe is not the prevalence

    The distance between population prevalence and effectively treatable patients is often an order of magnitude. How to build the funnel without inheriting unsourced figures.

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  • Methodological note · 2026

    Trackers that celebrate noise

    A three-point variation with n = 200 is almost never significant. What a brand tracker must report for the wave reading to be defensible.

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  • Analysis · 2025

    What the public sector changes in prescribing habit

    Averaging IMSS, ISSSTE, IMSS-Bienestar, state services and private destroys the most useful information in the study. Evidence for why sector stratification is mandatory in Mexico.

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  • Point of view · 2025

    The value dossier starts before the model

    Most evaluator observations are not about the economic model but about the evidence feeding it. How to order the file from the start.

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Full documents are sent by email on request. If a topic you care about is not on the list, say so and we will consider it for the next piece.

From the analysis to your study

If one of these notes describes a problem you have now, it is worth reviewing against your specific case.